Merck & Co Inc MRK

Morningstar Rating
$144.30 +0.49 (0.34%)
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Company Report

Merck's Large Late-Stage Pipeline Is Building Solid Defense Against Keytruda's Patent Cliff

Merck's combination of a wide lineup of high-margin drugs and a pipeline of new drugs should ensure strong returns on invested capital over the long term. While we expect the firm could see sales declines in the late 2020s as patents on core oncology drug Keytruda expire in the US, it is likely that pipeline launches will limit these declines to a roughly two-year period during 2029-30. On the pipeline front, after several years of only moderate research and development productivity, Merck's drug development strategy is yielding important new drugs.

Price vs Fair Value

MRK is trading at a LOCK|w@@V>q& premium.
Price
$143.81
Fair Value
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Uncertainty
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1-Star Price
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5-Star Price
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Economic Moat
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Capital Allocation
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Bulls Say, Bears Say

Bulls

Keytruda's leadership position in immuno-oncology, buoyed by a first-mover advantage in first-line non-small cell lung cancer, could become even further entrenched as Merck and other firms test new combinations with the drug.

Bears

The US patent loss on Keytruda in 2028 is concerning, given the high sales contribution of the drug (49% of 2025 sales).

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Trading Information

Previous Close Price
$143.81
Day Range
$142.73–144.35
52-Week Range
$82.01–156.92
Bid/Ask
$143.28 / $144.70
Shares Outstanding
2.47B
Market Cap
$356.01B
Volume/Avg
9M / 10M

Key Statistics

Price/Earnings (Normalized)
44.80
Price/Sales
5.36
Dividend Yield (Trailing)
2.36%
Dividend Yield (Forward)
2.36%
Dividend Payment Schedule
Jan, Apr, Jul, Oct
Total Yield
3.55%

Company Profile

Merck makes pharmaceutical products to treat several conditions in a number of therapeutic areas, including cardiometabolic disease, cancer, and infections. In cancer, the firm's immuno-oncology platform, led by Keytruda, is a major contributor to overall sales. The company also has a substantial vaccine business aimed at preventing pediatric diseases, as well as Gardasil for human papillomavirus. Additionally, Merck sells animal health-related drugs. From a geographical perspective, 53% of the company's 2025 sales were generated from US human health (pharmaceuticals and vaccines).
Sector
Healthcare
Industry
Drug Manufacturers - General
Stock Style Box
Large Value
Total Number of Employees
75,000

Competitors

Valuation

Metric
MRK
LLY
PFE
Price/Earnings (Normalized)
44.8036.519.22
Price/Book Value
8.4730.261.88
Price/Sales
5.3612.942.53
Price/Cash Flow
16.1031.3510.46
Price/Earnings
MRK
LLY
PFE

Financial Strength

Metric
MRK
LLY
PFE
Quick Ratio
0.710.680.85
Current Ratio
1.321.351.27
Interest Coverage
4.28—2.36
Quick Ratio
MRK
LLY
PFE

Profitability

Metric
MRK
LLY
PFE
Return on Assets (Normalized)
6.27%24.05%8.46%
Return on Equity (Normalized)
16.68%105.62%19.70%
Return on Invested Capital (Normalized)
9.82%39.55%12.66%
Return on Assets
MRK
LLY
PFE

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